Comparing Low-Dose Carvedilol Continuous Manufacturing by Solid and Liquid Feeding in Self-Emulsifying Delivery Systems via Hot Melt EXtrusion (SEDEX)

• Principais autores: Ožbej Zupančič (Autor), Josip Matić (Autor), Aygün Doğan (Autor), Alessio Gaggero (Autor), Johannes Khinast (Autor), Amrit Paudel (Autor)
• Formato: Livro
• Publicado em: MDPI AG, 2024-09-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

<b>Background/Objectives:</b> This study compared two pilot scale continuous manufacturing methods of solid self-emulsifying drug delivery systems (SEDDSs) via hot melt extrusion (HME). <b>Methods</b>: A model poorly water-soluble drug carvedilol in low dose (0.5-1.0% <i&g...