Role of GP82 in the selective binding to gastric mucin during oral infection with Trypanosoma cruzi.

• Main Authors: Daniela I Staquicini (Author), Rafael M Martins (Author), Silene Macedo (Author), Gisela R S Sasso (Author), Vanessa D Atayde (Author), Maria A Juliano (Author), Nobuko Yoshida (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Oral infection by Trypanosoma cruzi has been the primary cause of recent outbreaks of acute Chagas' diseases. This route of infection may involve selective binding of the metacyclic trypomastigote surface molecule gp82 to gastric mucin as a first step towards invasion of the gastric mucosal epi...