Taq-Polymerase Stop Assay to Determine Target Selectivity of G4 Ligands in Native Promoter Sequences of <i>MYC</i>, <i>TERT</i>, and <i>KIT</i> Oncogenes

Computational and high-throughput experimental methods predict thousands of potential quadruplex sequences (PQSs) in the human genome. Often these PQSs contain more than four G-runs, which introduce additional uncertainty into the conformational polymorphism of the G4 DNA. G4-specific ligands, which...

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Main Authors: Galina V. Chashchina (Author), Liana L. Tevonyan (Author), Artemy D. Beniaminov (Author), Dmitry N. Kaluzhny (Author)
Format: Book
Published: MDPI AG, 2023-04-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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