Controlled Delivery of BET-PROTACs: In Vitro Evaluation of MZ1-Loaded Polymeric Antibody Conjugated Nanoparticles in Breast Cancer

• मुख्य लेखकों: Francisco J. Cimas (लेखक), Enrique Niza (लेखक), Alberto Juan (लेखक), María del Mar Noblejas-López (लेखक), Iván Bravo (लेखक), Agustín Lara-Sanchez (लेखक), Carlos Alonso-Moreno (लेखक), Alberto Ocaña (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2020-10-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Bromo and extraterminal domain (BET) inhibitors-PROteolysis TArgeting Chimera (BETi-PROTAC) is a new family of compounds that induce proteasomal degradation through the ubiquitination of the tagged to BET inhibitors Bromodomain proteins, BRD2 and BRD. The encapsulation and controlled release of BET-...