Controlled Delivery of BET-PROTACs: In Vitro Evaluation of MZ1-Loaded Polymeric Antibody Conjugated Nanoparticles in Breast Cancer

• Päätekijät: Francisco J. Cimas (Tekijä), Enrique Niza (Tekijä), Alberto Juan (Tekijä), María del Mar Noblejas-López (Tekijä), Iván Bravo (Tekijä), Agustín Lara-Sanchez (Tekijä), Carlos Alonso-Moreno (Tekijä), Alberto Ocaña (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: MDPI AG, 2020-10-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Bromo and extraterminal domain (BET) inhibitors-PROteolysis TArgeting Chimera (BETi-PROTAC) is a new family of compounds that induce proteasomal degradation through the ubiquitination of the tagged to BET inhibitors Bromodomain proteins, BRD2 and BRD. The encapsulation and controlled release of BET-...