Effects of (−)‐MBP, a novel 5‐HT2C agonist and 5‐HT2A/2B antagonist/inverse agonist on brain activity: A phMRI study on awake mice

Effects of (−)‐MBP, a novel 5‐HT2C agonist and 5‐HT2A/2B antagonist/inverse agonist on brain activity: A phMRI study on awake mice

Abstract A novel serotonin ligand (−)‐MBP was developed for the treatment of schizophrenia that has 5‐HT2A/2B antagonist activity together with 5‐HT2C agonist activity. The multi‐functional activity of this novel drug candidate was characterized using pharmacological magnetic resonance imaging. It w...

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Main Authors: Preeti K. Sathe (Author), Gargi R. Ramdasi (Author), Kaylie Giammatteo (Author), Harvens Beauzile (Author), Shuyue Wang (Author), Heng Zhang (Author), Praveen Kulkarni (Author), Raymond G. Booth (Author), Craig F. Ferris (Author)
Format: Book
Published: Wiley, 2023-10-01T00:00:00Z.
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