3D-QSAR study and development of pharmacophore for serotonin 5-HT2A receptors agonists

• Main Authors: Radan Milica (Author), Nikolić Katarina (Author), Vučićević Jelica (Author), Oljačić Slavica (Author), Agbaba Danica (Author)
• Format: Book
• Published: Pharmaceutical Association of Serbia, Belgrade, Serbia, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

All tested compounds show agonistic activity onserotonin5-HT2areceptors, which activation causes neuronal excitations, behavioral changes and platelet aggregation. The main aims of this study were to create 3D-QSAR(3D-Quantitative structure-activity relationship)model, analyse 3D-structure of the ph...