Vorinostat Treatment of Gastric Cancer Cells Leads to ROS-Induced Cell Inhibition and a Complex Pattern of Molecular Alterations in Nrf2-Dependent Genes

• मुख्य लेखकों: Leoni Lorenz (लेखक), Tamara Zenz (लेखक), Denys Oliinyk (लेखक), Florian Meier-Rosar (लेखक), Robert Jenke (लेखक), Achim Aigner (लेखक), Thomas Büch (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2024-08-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Histone deacetylase inhibitors (HDACi) show high antineoplastic potential in preclinical studies in various solid tumors, including gastric carcinoma; however, their use in clinical studies has not yet yielded convincing efficacies. Thus, further studies on cellular/molecular effects of HDACi are ne...