Development and validation of a rapid chromatographic method for the analysis of flunarizine and its main production impurities

• Hoofdauteurs: Niamh OâConnor (Auteur), Michael Geary (Auteur), Mary Wharton (Auteur), Paul Sweetman (Auteur)
• Formaat: Boek
• Gepubliceerd in: Elsevier, 2013-06-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

A rapid selective method for the analysis of flunarizine and its associated impurities was developed and validated according to ICH guidelines. The separation was carried out using a Thermo Scientific Hypersil Gold C18 column (50mmÃ4.6mm i.d., 1.9μm particle size) with a gradient mobile phase of ac...