Tissue-plasminogen activator effects on the phenotype of splenic myeloid cells in acute inflammation

• Main Authors: Célia Seillier (Author), Léonie Lesec (Author), Pauline Hélie (Author), Charlotte Marie (Author), Denis Vivien (Author), Fabian Docagne (Author), Brigitte Le Mauff (Author), Olivier Toutirais (Author)
• Format: Book
• Published: BMC, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Tissue-plasminogen activator (tPA) is a serine protease well known for its fibrinolytic function. Recent studies indicate that tPA could also modulate inflammation via plasmin generation and/or by receptor mediated signalling in vitro. However, the contribution of tPA in inflammatory proces...