Tissue-plasminogen activator effects on the phenotype of splenic myeloid cells in acute inflammation

• المؤلفون الرئيسيون: Célia Seillier (مؤلف), Léonie Lesec (مؤلف), Pauline Hélie (مؤلف), Charlotte Marie (مؤلف), Denis Vivien (مؤلف), Fabian Docagne (مؤلف), Brigitte Le Mauff (مؤلف), Olivier Toutirais (مؤلف)
• التنسيق: كتاب
• منشور في: BMC, 2024-02-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Abstract Tissue-plasminogen activator (tPA) is a serine protease well known for its fibrinolytic function. Recent studies indicate that tPA could also modulate inflammation via plasmin generation and/or by receptor mediated signalling in vitro. However, the contribution of tPA in inflammatory proces...