Metabolic plasticity in a Pde6bSTOP/STOP retinitis pigmentosa mouse model following rescue

• Main Authors: Monika Ayten (Author), Nundehui Díaz-Lezama (Author), Hanaa Ghanawi (Author), Felia C. Haffelder (Author), Jacqueline Kajtna (Author), Tobias Straub (Author), Marco Borso (Author), Axel Imhof (Author), Stefanie M. Hauck (Author), Susanne F. Koch (Author)
• Format: Book
• Published: Elsevier, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Retinitis pigmentosa (RP) is a hereditary retinal disease characterized by progressive photoreceptor degeneration, leading to vision loss. The best hope for a cure for RP lies in gene therapy. However, given that RP patients are most often diagnosed in the midst of ongoing photoreceptor d...