Metabolic plasticity in a Pde6bSTOP/STOP retinitis pigmentosa mouse model following rescue

• Auteurs principaux: Monika Ayten (Auteur), Nundehui Díaz-Lezama (Auteur), Hanaa Ghanawi (Auteur), Felia C. Haffelder (Auteur), Jacqueline Kajtna (Auteur), Tobias Straub (Auteur), Marco Borso (Auteur), Axel Imhof (Auteur), Stefanie M. Hauck (Auteur), Susanne F. Koch (Auteur)
• Format: Livre
• Publié: Elsevier, 2024-10-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Objective: Retinitis pigmentosa (RP) is a hereditary retinal disease characterized by progressive photoreceptor degeneration, leading to vision loss. The best hope for a cure for RP lies in gene therapy. However, given that RP patients are most often diagnosed in the midst of ongoing photoreceptor d...