Sex differences in MAGEL2 gene promoter methylation in high functioning autism - trends from a pilot study using nanopore Cas9 targeted long read sequencing

• Main Authors: Jelte Wieting (Author), Kirsten Jahn (Author), Stefan Bleich (Author), Maximilian Deest (Author), Helge Frieling (Author)
• פורמט: ספר
• יצא לאור: BMC, 2024-11-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Abstract Background MAGEL2 is an autism susceptibility gene whose deficiency has been associated with autism-related behaviors in animal models and in syndromic human autism spectrum disorders (ASDs) such as Schaaf-Yang syndrome, but has not been studied in the broader autism spectrum. Given the cap...