A comparison of the bone and growth phenotype of mdx, mdx:Cmah−/− and mdx:Utrn+/− murine models with the C57BL/10 wild-type mouse

• Päätekijät: Claire L. Wood (Tekijä), Karla J. Suchacki (Tekijä), Rob van 't Hof (Tekijä), Will P. Cawthorn (Tekijä), Scott Dillon (Tekijä), Volker Straub (Tekijä), Sze Choong Wong (Tekijä), Syed F. Ahmed (Tekijä), Colin Farquharson (Tekijä), Annemieke Aartsma-Rus (Tekijä), James Dowling (Tekijä), Maaike van Putten (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: The Company of Biologists, 2020-02-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

The muscular dystrophy X-linked (mdx) mouse is commonly used as a mouse model of Duchenne muscular dystrophy (DMD). Its phenotype is, however, mild, and other mouse models have been explored. The mdx:Cmah−/− mouse carries a human-like mutation in the Cmah gene and has a severe muscle phenotype, but...