Phosphate-dependent FGF23 secretion is modulated by PiT2/Slc20a2

• প্রধান লেখক: Nina Bon (লেখক), Giulia Frangi (লেখক), Sophie Sourice (লেখক), Jérôme Guicheux (লেখক), Sarah Beck-Cormier (লেখক), Laurent Beck (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Elsevier, 2018-05-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Objective: The canonical role of the bone-derived fibroblast growth factor 23 (Fgf23) is to regulate the serum inorganic phosphate (Pi) level. As part of a feedback loop, serum Pi levels control Fgf23 secretion through undefined mechanisms. We recently showed in vitro that the two high-affinity Na+-...