Phosphate-dependent FGF23 secretion is modulated by PiT2/Slc20a2

• Główni autorzy: Nina Bon (Autor), Giulia Frangi (Autor), Sophie Sourice (Autor), Jérôme Guicheux (Autor), Sarah Beck-Cormier (Autor), Laurent Beck (Autor)
• Format: Książka
• Wydane: Elsevier, 2018-05-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Objective: The canonical role of the bone-derived fibroblast growth factor 23 (Fgf23) is to regulate the serum inorganic phosphate (Pi) level. As part of a feedback loop, serum Pi levels control Fgf23 secretion through undefined mechanisms. We recently showed in vitro that the two high-affinity Na+-...