Repurposing of Plasminogen: An Orphan Medicinal Product Suitable for SARS-CoV-2 Inhalable Therapeutics

• Main Authors: Anna Maria Piras (Author), Ylenia Zambito (Author), Maurizio Lugli (Author), Baldassare Ferro (Author), Paolo Roncucci (Author), Filippo Mori (Author), Alfonso Salvatore (Author), Ester Ascione (Author), Marta Bellini (Author), Roberto Crea (Author)
• Format: Book
• Published: MDPI AG, 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The SARS-CoV-2 infection is associated with pulmonary coagulopathy, which determines the deposition of fibrin in the air spaces and lung parenchyma. The resulting lung lesions compromise patient pulmonary function and increase mortality, or end in permanent lung damage for those who have recovered f...