Prediction of Pharmacokinetics of IDP-73152 in Humans Using Physiologically-Based Pharmacokinetics

IDP-73152, a novel peptide deformylase inhibitor with an antibacterial effect against Gram-positive bacteria, is in phase I development. The objective of this study was to develop a physiologically-based pharmacokinetic model (PBPK) for IDP-73152 in animals, and to extend the model to humans. Biopha...

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Main Authors: Myongjae Lee (Author), Yoo-Seong Jeong (Author), Min-Soo Kim (Author), Kyung-Mi An (Author), Suk-Jae Chung (Author)
Format: Book
Published: MDPI AG, 2022-05-01T00:00:00Z.
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