Luteolin Ameliorates Experimental Pulmonary Arterial Hypertension via Suppressing Hippo-YAP/PI3K/AKT Signaling Pathway

• Main Authors: Wanyun Zuo (Author), Na Liu (Author), Yunhong Zeng (Author), Zhenghui Xiao (Author), Keke Wu (Author), Fan Yang (Author), Biao Li (Author), Qingqing Song (Author), Yunbin Xiao (Author), Qiming Liu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Luteolin is a flavonoid compound with a variety of pharmacological effects. In this study, we explored the effects of luteolin on monocrotaline (MCT) induced rat pulmonary arterial hypertension (PAH) and underlying mechanisms. A rat PAH model was generated through MCT injection. In this model, luteo...