The cell fate regulator NUPR1 is induced by Mycobacterium leprae via type I interferon in human leprosy.

• Main Authors: Priscila R Andrade (Author), Manali Mehta (Author), Jing Lu (Author), Rosane M B Teles (Author), Dennis Montoya (Author), Phillip O Scumpia (Author), Euzenir Nunes Sarno (Author), Maria Teresa Ochoa (Author), Feiyang Ma (Author), Matteo Pellegrini (Author), Robert L Modlin (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The initial interaction between a microbial pathogen and the host immune response influences the outcome of the battle between the host and the foreign invader. Leprosy, caused by the obligate intracellular pathogen Mycobacterium leprae, provides a model to study relevant human immune responses. Pre...