The cell fate regulator NUPR1 is induced by Mycobacterium leprae via type I interferon in human leprosy.

• Autors principals: Priscila R Andrade (Autor), Manali Mehta (Autor), Jing Lu (Autor), Rosane M B Teles (Autor), Dennis Montoya (Autor), Phillip O Scumpia (Autor), Euzenir Nunes Sarno (Autor), Maria Teresa Ochoa (Autor), Feiyang Ma (Autor), Matteo Pellegrini (Autor), Robert L Modlin (Autor)
• Format: Llibre
• Publicat: Public Library of Science (PLoS), 2019-07-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

The initial interaction between a microbial pathogen and the host immune response influences the outcome of the battle between the host and the foreign invader. Leprosy, caused by the obligate intracellular pathogen Mycobacterium leprae, provides a model to study relevant human immune responses. Pre...