Development, testing, parameterisation, and calibration of a human PBK model for the plasticiser, di (2-ethylhexyl) adipate (DEHA) using in silico, in vitro and human biomonitoring data

Introduction: A physiologically based biokinetic model for di (2-ethylhexyl) adipate (DEHA) based on a refined model for di-(2-propylheptyl) phthalate (DPHP) was developed to interpret the metabolism and biokinetics of DEHA following a single oral dosage of 50 mg to two male and two female volunteer...

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Hauptverfasser: Kevin McNally (Verfasst von), Craig Sams (Verfasst von), George Loizou (Verfasst von)
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Veröffentlicht: Frontiers Media S.A., 2023-03-01T00:00:00Z.
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