Circulating EVs long RNA-based subtyping and deconvolution enable prediction of immunogenic signatures and clinical outcome for PDAC

• Main Authors: Yuchen Li (Author), Ye Li (Author), Shulin Yu (Author), Ling Qian (Author), Kun Chen (Author), Hongyan Lai (Author), Hena Zhang (Author), Yan Li (Author), Yalei Zhang (Author), Sijia Gu (Author), Zhiqiang Meng (Author), Shenglin Huang (Author), Peng Wang (Author)
• Format: Knjiga
• Izdano: Elsevier, 2021-12-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Identification of clinically applicable molecular subtypes of pancreatic ductal adenocarcinoma (PDAC) is crucial to improving patient outcomes. However, the traditional tissue-dependent transcriptional subtyping strategies are invasive and not amenable to routine clinical evaluation. In this study,...