Genome-wide DNA methylation profiling of CD4+ T lymphocytes identifies differentially methylated loci associated with adult primary refractory immune thrombocytopenia

• প্রধান লেখক: Hanzhi Du (লেখক), Qinghua Tang (লেখক), Jian Yang (লেখক), Bin Yan (লেখক), Lihong Yang (লেখক), Mengchang Wang (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: BMC, 2023-06-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Abstract Background DNA methylation played a crucial role in the pathogenesis of immune thrombocytopenia (ITP). However, genome-wide DNA methylation analysis has not been applied thus far. The present study aimed to provide the first DNA methylation profiling for ITP. Methods Peripheral blood CD4+ T...