Genome-wide DNA methylation profiling of CD4+ T lymphocytes identifies differentially methylated loci associated with adult primary refractory immune thrombocytopenia

• Main Authors: Hanzhi Du (Author), Qinghua Tang (Author), Jian Yang (Author), Bin Yan (Author), Lihong Yang (Author), Mengchang Wang (Author)
• Formato: Livro
• Publicado em: BMC, 2023-06-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Background DNA methylation played a crucial role in the pathogenesis of immune thrombocytopenia (ITP). However, genome-wide DNA methylation analysis has not been applied thus far. The present study aimed to provide the first DNA methylation profiling for ITP. Methods Peripheral blood CD4+ T...