Postbiotic muramyl dipeptide alleviates colitis via activating autophagy in intestinal epithelial cells

• Main Authors: Yaying You (Author), Yongtao Xiao (Author), Ying Lu (Author), Jun Du (Author), Hui Cai (Author), Wei Cai (Author), Weihui Yan (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The pathogenesis of IBD is complicated and still unclear. Nucleotide-binding oligomerization domain 2 (NOD2) plays a significant role in regulating gut inflammation under the activation of muramyl dipeptide (MDP), which is used as a postbiotic. The study aimed to investigate the effect of MDP on the...