A Quasi-Physiological Microfluidic Blood-Brain Barrier Model for Brain Permeability Studies

• Autori principali: Behnam Noorani (Autore), Aditya Bhalerao (Autore), Snehal Raut (Autore), Ehsan Nozohouri (Autore), Ulrich Bickel (Autore), Luca Cucullo (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2021-09-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Microfluidics-based organ-on-a-chip technology allows for developing a new class of in-vitro blood-brain barrier (BBB) models that recapitulate many hemodynamic and architectural features of the brain microvasculature not attainable with conventional two-dimensional platforms. Herein, we describe an...