A Lanosteryl triterpene from Protorhus longifolia augments insulin signaling in type 1 diabetic rats

• Main Authors: Sihle Ephraim Mabhida (Author), Rabia Johnson (Author), Musawenkosi Ndlovu (Author), Nonhlakanipho Felicia Sangweni (Author), Johan Louw (Author), Andrew Opoku (Author), Rebamang Anthony Mosa (Author)
• Format: Book
• Published: BMC, 2018-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background A substantial literature supports antidiabetic properties of the lanosteryl triterpene (methyl-3β-hydroxylanosta-9,24-dien-21-oate, RA-3) isolated from Protorhus longifolia stem bark. However, the molecular mechanism(s) associated with the antihyperglycemic properties of the trit...