Adult‐type granulosa cell tumor of the ovary: a FOXL2‐centric disease

• Main Authors: Jessica A Pilsworth (Author), Dawn R Cochrane (Author), Samantha J Neilson (Author), Bahar H Moussavi (Author), Daniel Lai (Author), Aslı D Munzur (Author), Janine Senz (Author), Yi Kan Wang (Author), Sina Zareian (Author), Ali Bashashati (Author), Adele Wong (Author), Jacqueline Keul (Author), Annette Staebler (Author), Hannah S vanMeurs (Author), Hugo M Horlings (Author), Stefan Kommoss (Author), Friedrich Kommoss (Author), Esther Oliva (Author), Anniina EM Färkkilä (Author), Blake Gilks (Author), David G Huntsman (Author)
• Format: Book
• Published: Wiley, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Adult‐type granulosa cell tumors (aGCTs) account for 90% of malignant ovarian sex cord‐stromal tumors and 2-5% of all ovarian cancers. These tumors are usually diagnosed at an early stage and are treated with surgery. However, one‐third of patients relapse between 4 and 8 years after initia...