Coamorphous Atorvastatin Calcium to Improve its Physicochemical and Pharmacokinetic Properties

• Váldodahkkit: Ali Shayanfar (Dahkki), Hamed Ghavimi (Dahkki), Hamed Hamishekar (Dahkki), Abolghasem Jouyban (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Frontiers Media S.A., 2013-10-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Purpose: Atorvastatin calcium (ATC) is classified as class II (low solubility and high permeability) compound according to the biopharmaceutical classification system. The amorphous form of ATC possesses higher solubility, dissolution rate, and bioavailability than its crystalline form. Coamorphous...