Epigenetic Induction of Definitive and Pancreatic Endoderm Cell Fate in Human Fibroblasts
Reprogramming can occur by the introduction of key transcription factors (TFs) as well as by epigenetic changes. We demonstrated that histone deacetylase inhibitor (HDACi) Trichostatin A (TSA) combined with a chromatin remodeling medium (CRM) induced expression of a number of definitive endoderm and...
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| Main Authors: | , , , , , |
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| Format: | Book |
| Published: |
Hindawi Limited,
2016-01-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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