Epigenetic Induction of Definitive and Pancreatic Endoderm Cell Fate in Human Fibroblasts

Reprogramming can occur by the introduction of key transcription factors (TFs) as well as by epigenetic changes. We demonstrated that histone deacetylase inhibitor (HDACi) Trichostatin A (TSA) combined with a chromatin remodeling medium (CRM) induced expression of a number of definitive endoderm and...

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Main Authors: Rangarajan Sambathkumar (Author), Eric Kalo (Author), Rob Van Rossom (Author), Marijke M. Faas (Author), Paul de Vos (Author), Catherine M. Verfaillie (Author)
Format: Book
Published: Hindawi Limited, 2016-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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