Inhibition of the STAT3 Signaling Pathway Contributes to the Anti-Melanoma Activities of Shikonin

• Main Authors: Hui-Hui Cao (Author), Dong-Yi Liu (Author), Ye-Cai Lai (Author), Yu-Yao Chen (Author), Lin-Zhong Yu (Author), Meng Shao (Author), Jun-Shan Liu (Author)
• Format: Knjiga
• Izdano: Frontiers Media S.A., 2020-05-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

BackgroundMalignant melanoma is an extremely aggressive and metastatic cancer, and highly resistant to conventional therapies. Signal transducer and activator of transcription 3 (STAT3) signaling promotes melanoma development and progression, which has been validated as an effective target in melano...