Design and optimization of piperidine-substituted thiophene[3,2-d]pyrimidine-based HIV-1 NNRTIs with improved drug resistance and pharmacokinetic profiles

HIV-1 reverse transcriptase (RT) has received great attention as an attractive therapeutic target for acquired immune deficiency syndrome (AIDS), but the inevitable drug resistance and side effects have always been major challenges faced by non-nucleoside reverse transcriptase inhibitors (NNRTIs). T...

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ग्रंथसूची विवरण
मुख्य लेखकों: Yanying Sun (लेखक), Zhenzhen Zhou (लेखक), Zhongling Shi (लेखक), Fabao Zhao (लेखक), Minghui Xie (लेखक), Zongji Zhuo (लेखक), Erik De Clercq (लेखक), Christophe Pannecouque (लेखक), Dongwei Kang (लेखक), Peng Zhan (लेखक), Xinyong Liu (लेखक)
स्वरूप: पुस्तक
प्रकाशित: Elsevier, 2024-07-01T00:00:00Z.
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