A Novel HNF4A Mutation Causing Three Phenotypic Forms of Glucose Dysregulation in a Family

• Autores principales: Suresh Chandran (Autor), Victor Samuel Rajadurai (Autor), Wai Han Hoi (Autor), Sarah E. Flanagan (Autor), Khalid Hussain (Autor), Fabian Yap (Autor)
• Formato: Libro
• Publicado: Frontiers Media S.A., 2020-06-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Maturity-onset diabetes of the young (MODY) classically describes dominantly inherited forms of monogenic diabetes diagnosed before 25 years of age due to pancreatic β-cell dysfunction. In contrast, mutations in certain MODY genes can also present with transient or persistent hyperinsulinemic hypogl...