Non-small molecule PROTACs (NSM-PROTACs): Protein degradation kaleidoscope

• Main Authors: Sinan Ma (Author), Jianai Ji (Author), Yuanyuan Tong (Author), Yuxuan Zhu (Author), Junwei Dou (Author), Xian Zhang (Author), Shicheng Xu (Author), Tianbao Zhu (Author), Xiaoli Xu (Author), Qidong You (Author), Zhengyu Jiang (Author)
• Format: Book
• Published: Elsevier, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The proteolysis targeting chimeras (PROTACs) technology has been rapidly developed since its birth in 2001, attracting rapidly growing attention of scientific institutes and pharmaceutical companies. At present, a variety of small molecule PROTACs have entered the clinical trial. However, as small m...