Malignant transformation of white sponge nevus: a case report of a novel keratin 4 mutation

• Main Authors: Dan Liu (Author), Tianyu Zhang (Author), Hangfan Zhou (Author), Chuanji Wu (Author), Taiwen Li (Author), Lu Jiang (Author)
• Format: Book
• Published: BMC, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background White Sponge Nevus (WSN) is traditionally considered a benign genetic disorder affecting the oral mucosa, primarily caused by pathogenic mutations in keratin 4 (KRT4) or keratin 13 (KRT13). Despite its benign nature, recent evidence has begun to question the malignant potential o...