Toxicokinetics of a humanized anti-cocaine monoclonal antibody in male and female rats and lack of cross-reactivity
ABSTRACTA humanized monoclonal antibody h2E2 designed to bind cocaine with high affinity, specificity, and a long half-life (~7 d in rats) is being developed as a treatment for cocaine use disorder. We report here a pharmacokinetic (PK) study of h2E2 using male and female rats conducted under a Good...
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Format: | Book |
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Taylor & Francis Group,
2023-12-01T00:00:00Z.
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A1234.567 |
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Copy 1 | Available |