Permeability of the Retina and RPE-Choroid-Sclera to Three Ophthalmic Drugs and the Associated Factors

• Main Authors: Hyeong Min Kim (Author), Hyounkoo Han (Author), Hye Kyoung Hong (Author), Ji Hyun Park (Author), Kyu Hyung Park (Author), Hyuncheol Kim (Author), Se Joon Woo (Author)
• Format: Book
• Published: MDPI AG, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In this study, Retina-RPE-Choroid-Sclera (RCS) and RPE-Choroid-Sclera (CS) were prepared by scraping them off neural retina, and using the Ussing chamber we measured the average time-concentration values in the acceptor chamber across five isolated rabbit tissues for each drug molecule. We determine...