Optimized Dosing Regimens of Meropenem in Septic Children Receiving Extracorporeal Life Support

• Κύριοι συγγραφείς: Yixue Wang (Συγγραφέας), Weiming Chen (Συγγραφέας), Yidie Huang (Συγγραφέας), Guangfei Wang (Συγγραφέας), Zhiping Li (Συγγραφέας), Gangfeng Yan (Συγγραφέας), Chao Chen (Συγγραφέας), Guoping Lu (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Objectives: To develop a population pharmacokinetic model of meropenem in children with sepsis receiving extracorporeal life support (ECLS) and optimize the dosage regimen based on investigating the probability of target attainment (PTA).Methods: The children with sepsis were prospectively enrolled...