Optimized Dosing Regimens of Meropenem in Septic Children Receiving Extracorporeal Life Support

• Main Authors: Yixue Wang (Author), Weiming Chen (Author), Yidie Huang (Author), Guangfei Wang (Author), Zhiping Li (Author), Gangfeng Yan (Author), Chao Chen (Author), Guoping Lu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: To develop a population pharmacokinetic model of meropenem in children with sepsis receiving extracorporeal life support (ECLS) and optimize the dosage regimen based on investigating the probability of target attainment (PTA).Methods: The children with sepsis were prospectively enrolled...