Molecular Determinants Responsible for Sedative and Non-sedative Properties of Histamine H1-Receptor Antagonists
There is argument whether non-sedative properties of histamine H1-receptor antagonists (antihistamines) are determined by their active extrusions from the brain via P-glycoprotein or their restricted penetration through the blood-brain barrier. We have reported that sedative and non-sedative antihis...
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Main Authors: | Yoshihiro Uesawa (Author), Shigeru Hishinuma (Author), Masaru Shoji (Author) |
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Format: | Book |
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Elsevier,
2014-01-01T00:00:00Z.
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