Mechanism of cancer-induced bone destruction: An association of connective tissue growth factor (CTGF/CCN2) in the bone metastasis

• المؤلفون الرئيسيون: Tsuyoshi Shimo (مؤلف), Akira Sasaki (مؤلف)
• التنسيق: كتاب
• منشور في: Elsevier, 2011-02-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Connective tissue growth factor (CTGF/CCN2) is a member of the CCN family, a novel class of extracellular signal modulators. CCN2 is composed of four conserved modules connected in tandem, each of which is rich in cysteines and highly interactive with other molecules. CCN2 has various biological fun...