Effect of theaflavin-3,3'-digallate on leptin-deficient induced nonalcoholic fatty liver disease might be related to lipid metabolism regulated by the Fads1/PPARδ/Fabp4 axis and gut microbiota

• Main Authors: Cheng Zhou (Author), Wenji Zhang (Author), Hui Lin (Author), Luyun Zhang (Author), Fan Wu (Author), Yan Wang (Author), Susu Yu (Author), Xinyue Peng (Author), Wenli Cheng (Author), Min Li (Author), Xiaoying Pan (Author), Zhenrui Huang (Author), Wenjuan Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nonalcoholic fatty liver disease (NAFLD), one of the risk factors for hepatitis, cirrhosis, and even hepatic carcinoma, has been a global public health problem. The polyphenol compound theaflavin-3,3'-digallate (TF3), mainly extracted from black tea, has been reported to produce an effect on hy...