Structural Characterization of TRAF6 N-Terminal for Therapeutic Uses and Computational Studies on New Derivatives

• Main Authors: Omur Guven (Author), Belgin Sever (Author), Faika Başoğlu-Ünal (Author), Abdulilah Ece (Author), Hiroshi Tateishi (Author), Ryoko Koga (Author), Mohamed O. Radwan (Author), Nefise Demir (Author), Mustafa Can (Author), Mutlu Dilsiz Aytemir (Author), Jun-ichiro Inoue (Author), Masami Otsuka (Author), Mikako Fujita (Author), Halilibrahim Ciftci (Author), Hasan DeMirci (Author)
• Format: Book
• Published: MDPI AG, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tumor necrosis factor receptor-associated factors (TRAFs) are a protein family with a wide variety of roles and binding partners. Among them, TRAF6, a ubiquitin ligase, possesses unique receptor binding specificity and shows diverse functions in immune system regulation, cellular signaling, central...