Identification of a novel ESR1 mutation in a Chinese PCOS woman with estrogen insensitivity in IVF treatment

• Main Authors: Faying Liu (Author), Lifeng Tian (Author), Jun Tan (Author), Zengming Li (Author), Haiyan Qin (Author), Dingfei Xu (Author), Zhihui Huang (Author), Xingwu Wu (Author), Ge Chen (Author), Qiongfang Wu (Author), Yang Zou (Author)
• Format: Book
• Published: BMC, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Polycystic ovary syndrome (PCOS) is a complex reproductive disorder, that affects approximately 5-10% of women of reproductive age. The disease is complex because its evolution may be impacted by genetic, lifestyle and environmental factors. Previous studies have emphasized the i...