PGC-1α expression in murine AgRP neurons regulates food intake and energy balance

• Prif Awduron: Jonathan F. Gill (Awdur), Julien Delezie (Awdur), Gesa Santos (Awdur), Christoph Handschin (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Elsevier, 2016-07-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Objective: Food intake and whole-body energy homeostasis are controlled by agouti-related protein (AgRP) and pro-opiomelanocortin (POMC) neurons located in the arcuate nucleus of the hypothalamus. Key energy sensors, such as the AMP-activated protein kinase (AMPK) or sirtuin 1 (SIRT1), are essential...