Tumour necrosis factor-alpha (TNFα) stimulates the growth of human bone marrow stromal cells

• Main Authors: F. Rougier (Author), E. Cornu (Author), N. Gachard (Author), V. Praloran (Author), Y. Denizot (Author)
• Format: Book
• Published: Hindawi Limited, 1997-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study reports that TNF-α is a potent mitogen for human bone marrow sternal cells in vitro (assessed by [3H]-thymidine incorporation into DNA and cell counts). In contrast, cytokines such as IL-1α, IL-1β, IL-2, IL-3, IL-4, IL-6, LIF, SCF, M-CSF, G-CSF and GM-CSF had no effect. The effect of TNF-...