Impact of high drinking water nitrate levels on the endogenous formation of apparent N-nitroso compounds in combination with meat intake in healthy volunteers

• Main Authors: Simone G. van Breda (Author), Karen Mathijs (Author), Virág Sági-Kiss (Author), Gunter G. Kuhnle (Author), Ben van der Veer (Author), Rena R. Jones (Author), Rashmi Sinha (Author), Mary H. Ward (Author), Theo M. de Kok (Author)
• Format: Book
• Published: BMC, 2019-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Nitrate is converted to nitrite in the human body and subsequently can react with amines and amides in the gastrointestinal tract to form N-nitroso compounds (NOCs), which are known to be carcinogenic in animals. Humans can be exposed to nitrate via consumption of drinking water...