Pharmacodynamics of the Glutamate Receptor Antagonists in the Rat Barrel Cortex

• Egile Nagusiak: Daria Vinokurova (Egilea), Andrey V. Zakharov (Egilea), Julia Lebedeva (Egilea), Gulshat F. Burkhanova (Egilea), Kseniya A. Chernova (Egilea), Nailya Lotfullina (Egilea), Rustem Khazipov (Egilea), Guzel Valeeva (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2018-07-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Epipial application is one of the approaches for drug delivery into the cortex. However, passive diffusion of epipially applied drugs through the cortical depth may be slow, and different drug concentrations may be achieved at different rates across the cortical depth. Here, we explored the pharmaco...