Sulfocoumarins as dual inhibitors of human carbonic anhydrase isoforms IX/XII and of human thioredoxin reductase

The hypothesis that sulfocoumarin acting as inhibitors of human carbonic anhydrase (CA, EC 4.2.1.1) cancer-associated isoforms hCA IX and - hCA XII is being able to also inhibit thioredoxin reductase was verified and confirmed. The dual targeting of two cancer cell defence mechanisms, i.e. hypoxia a...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Mikhail Krasavin (लेखक), Raivis Žalubovskis (लेखक), Aiga Grandāne (लेखक), Ilona Domračeva (लेखक), Petr Zhmurov (लेखक), Claudiu T. Supuran (लेखक)
स्वरूप: पुस्तक
प्रकाशित: Taylor & Francis Group, 2020-01-01T00:00:00Z.
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3rd Floor Main Library

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