Rationale and design of two prospective, multicenter, observational studies on reproductive outcome in women with recurrent failures after spontaneous or assisted conception: OTTILIA and FIRST registries

• Main Authors: Michela Villani (Author), Domenico Baldini (Author), Pasquale Totaro (Author), Giovanni Larciprete (Author), Mirjana Kovac (Author), Domenico Carone (Author), Serena Maria Passamonti (Author), Eleonora Tamborini Permunian (Author), Tiziana Bartolotti (Author), Andrea Lojacono (Author), Rossella Cacciola (Author), Giuliano Lo Pinto (Author), Eugenio Bucherini (Author), Valerio De Stefano (Author), Corrado Lodigiani (Author), Cristina Lavopa (Author), Yoon Sung Cho (Author), Caterina Pizzicaroli (Author), Donatella Colaizzo (Author), Elvira Grandone (Author)
• Format: Book
• Published: BMC, 2019-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Spontaneous pregnancy loss and implantation failure after assisted reproductive technologies (ART) are very common occurrences. Although 50-60% of all cases remains unexplained, various predisposing factors, including thrombophilias, have been identified. Thus, the potential bene...