Drug-drug interactions between pemafibrate and statins on pharmacokinetics in healthy male volunteers: Open‐label, randomized, 6‐sequence, 3‐period crossover studies

• Main Authors: Tomohiro Kamimura (Author), Neil Hounslow (Author), Hideki Suganami (Author), Ryohei Tanigawa (Author)
• Formato: Livro
• Publicado em: Wiley, 2024-08-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Elevated triglyceride levels are associated with an increased risk of cardiovascular events despite guideline‐based statin treatment of low‐density lipoprotein cholesterol. Peroxisome proliferator‐activated receptor α (PPARα) agonists exert a significant triglyceride‐lowering effect. Howeve...