SPO11-C631T Gene Polymorphism: Association With Male Infertility and an in Silico-Analysis

• Main Authors: Mohammad Karimian (Author), Hossein Nikzad (Author), Abolfazl Azami-Tameh (Author), Aliakbar Taherian (Author), Fatemeh Zahra Darvishi (Author), Mohammad Javad Haghighatnia (Author)
• Format: Book
• Published: Tehran University of Medical Sciences, 2016-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: To investigate the association of C631T single nucleotide polymorphisms in SPO11 gene with male infertilityfollowed by an in silico approach. SPO11 is a gene involved in meiosis and spermatogenesis process, which in humans, this gene is located on chromosome 20 (20q13.2-13.3) with 13 exon...