Receptor activity-modifying protein modulation of parathyroid hormone-1 receptor function and signaling

• Main Authors: Paris Avgoustou (Author), Ameera B. A. Jailani (Author), Aditya J. Desai (Author), David J. Roberts (Author), Ewan R. Lilley (Author), Grant W. Stothard (Author), Timothy M. Skerry (Author), Gareth O. Richards (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

IntroductionReceptor activity-modifying proteins (RAMPs) are known to modulate the pharmacology and function of several G-protein-coupled receptors (GPCRs), including the parathyroid hormone 1 receptor (PTH1R). However, the precise effects of different RAMPs on PTH1R signalling and trafficking remai...