Receptor activity-modifying protein modulation of parathyroid hormone-1 receptor function and signaling

• Auteurs principaux: Paris Avgoustou (Auteur), Ameera B. A. Jailani (Auteur), Aditya J. Desai (Auteur), David J. Roberts (Auteur), Ewan R. Lilley (Auteur), Grant W. Stothard (Auteur), Timothy M. Skerry (Auteur), Gareth O. Richards (Auteur)
• Format: Livre
• Publié: Frontiers Media S.A., 2024-09-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

IntroductionReceptor activity-modifying proteins (RAMPs) are known to modulate the pharmacology and function of several G-protein-coupled receptors (GPCRs), including the parathyroid hormone 1 receptor (PTH1R). However, the precise effects of different RAMPs on PTH1R signalling and trafficking remai...