Dual-Target Compounds against Type 2 <i>Diabetes Mellitus</i>: Proof of Concept for Sodium Dependent Glucose Transporter (SGLT) and Glycogen Phosphorylase (GP) Inhibitors

• Main Authors: Ádám Sipos (Author), Eszter Szennyes (Author), Nikolett Éva Hajnal (Author), Sándor Kun (Author), Katalin E. Szabó (Author), Karen Uray (Author), László Somsák (Author), Tibor Docsa (Author), Éva Bokor (Author)
• Format: Book
• Published: MDPI AG, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A current trend in the quest for new therapies for complex, multifactorial diseases, such as diabetes mellitus (DM), is to find dual or even multi-target inhibitors. In DM, the sodium dependent glucose cotransporter 2 (SGLT2) in the kidneys and the glycogen phosphorylase (GP) in the liver are valida...